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PESTILENCE WATCH:Pandemic flu plan would put Chicago on lockdown

CHICAGO-Containing an influenza pandemic in a large U.S. city like Chicago would require widespread school closings, quarantines of infected households and bans on public gatherings,U.S. researchers said on Monday.But, if done quickly and well, such steps could reduce infections by as much as 80 percent, said researcher Stephen Eubank of Virginia Tech in Blacksburg, Virginia, based on a computer simulation of just such an event."If you implement it early and people comply, you can save a lot of people. You can make it look a lot more like a seasonal flu than the 1918 pandemic," said Eubank, referring to a global flu epidemic that started in 1918 and killed between 40 million and 100 million people.Health experts almost universally agree that a global epidemic-a pandemic-of influenza is inevitable.Flu is always circulating but, every few decades, a completely new strain emerges and makes millions sicker than usual.Government estimates suggest vaccines and drugs will not be enough to slow or prevent a flu pandemic, and the U.S. pandemic plan includes ways to limit the spread by closing schools and implementing strategies to reduce contact with infected people.Eubank led one of three teams of scientists who ran computer simulations to see if drug and social containment efforts could slow the spread of an influenza pandemic in a major U.S. city such as Chicago, which has a population of about 8.6 million people.All three teams found that a combination of antiviral drugs-such as Roche AG and Gilead Sciences Inc.'s Tamiflu-and social distancing efforts would be needed to slow the spread of a pandemic flu,they report in the Proceedings of the National Academy of Sciences."Depending on how fast it is spreading, it seems as though you really need to throw everything you can at it," Eubank said in a telephone interview.
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